Alloimmunization Prevents the Migration of Transfused Indium - ill - Labeled Granulocytes to Sites of Infection
نویسندگان
چکیده
“In-labeled granulocytes were used to study the effects of histocompatibility factors on the migration of transfused granulocytes to infected sites. Fourteen alloimmunized and 20 nonalloimmunized patients received approximately 108 “In-labeled granulocytes from ABO-compatible. non-HIAmatched donors. and scans were performed over known infected sites. All 14 alloimmunized patients had lymphocytotoxic antibody (ICTAb) and required HLA-matched platelet transfusions. Of the nonalloimmunized patients. 20/20 had positive scans at sites of infection. None of the 20 had LCTAb. 0/ 1 7 had a positive lymphocytotoxic crossmatch (LCTXM) with the donor. and 3/18 had a positive leukoagglutinin crossmatch (LAXM). Thus. histocompatibility testing was not found to be important in nonalloimmunized
منابع مشابه
Alloimmunization prevents the migration of transfused indium-111-labeled granulocytes to sites of infection.
111In-labeled granulocytes were used to study the effects of histocompatibility factors on the migration of transfused granulocytes to infected sites. Fourteen alloimmunized and 20 nonalloimmunized patients received approximately 10(8) 111In-labeled granulocytes from ABO-compatible, non-HLA-matched donors, and scans were performed over known infected sites. All 14 alloimmunized patients had lym...
متن کاملAlloimmunization Prevents the Migration of Transfused
“In-labeled granulocytes were used to study the effects of histocompatibility factors on the migration of transfused granulocytes to infected sites. Fourteen alloimmunized and 20 nonalloimmunized patients received approximately 108 “In-labeled granulocytes from ABO-compatible. non-HIAmatched donors. and scans were performed over known infected sites. All 14 alloimmunized patients had lymphocyto...
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